The Horn of Africa is one of the world’s most challenging regions for security and development. It is also a highly significant geostrategic site. This report uses the International Futures modelling platform to analyse current and future development pathways to 2040 for Djibouti, Eritrea, Ethiopia, Somalia, Sudan and South Sudan. A presentation of these countries’ current development trajectories is followed by a discussion of alternative sectoral approaches to achieving inclusive, sustainable growth and development.